发明申请
US20120195830A1 Monoclonal Antibodies Against Claudin-18 For Treatment of Cancer
有权
针对Claudin-18的单克隆抗体用于治疗癌症
- 专利标题： Monoclonal Antibodies Against Claudin-18 For Treatment of Cancer
- 专利标题（中）： 针对Claudin-18的单克隆抗体用于治疗癌症
-
申请号： US13425538申请日： 2012-03-21
-
公开(公告)号： US20120195830A1公开(公告)日： 2012-08-02
- 发明人: Ugur Sahin , Özlem Türeci , Dirk Usener , Stefan Fritz , Christoph Uherek , Gunda Brandenburg , Harald-Gerhard Geppert , Anja Kristina Schröder , Phillippe Thiel
- 申请人： Ugur Sahin , Özlem Türeci , Dirk Usener , Stefan Fritz , Christoph Uherek , Gunda Brandenburg , Harald-Gerhard Geppert , Anja Kristina Schröder , Phillippe Thiel
- 申请人地址： DE MAINZ DE MAINZ
- 专利权人： JOHANNES GUTENBERG-UNIVERSITAT MAINZ,GANYMED PHARMACEUTICALS AG
- 当前专利权人： JOHANNES GUTENBERG-UNIVERSITAT MAINZ,GANYMED PHARMACEUTICALS AG
- 当前专利权人地址： DE MAINZ DE MAINZ
- 优先权： EP05025657.7 20051124
- 主分类号： A61K51/10
- IPC分类号： A61K51/10 ; A61P35/00 ; A61K39/395 ; C07K16/30 ; C12N5/16
摘要：
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD18, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder.