发明申请
- 专利标题： GABA RELEASE-REGULATING AGENT IN CEREBELLUM
- 专利标题（中）： GABA释放调节剂在CEREBELLUM
-
申请号： US13389981申请日： 2010-08-24
-
公开(公告)号： US20120214742A1公开(公告)日： 2012-08-23
- 发明人: Changjoon Justin Lee , Soo-Jung Lee , Bo-Eun Yoon
- 申请人： Changjoon Justin Lee , Soo-Jung Lee , Bo-Eun Yoon
- 优先权： KR10-2009-0077979 20090824
- 国际申请： PCT/KR10/05653 WO 20100824
- 主分类号： A61K38/08
- IPC分类号： A61K38/08 ; A61K31/7105 ; C07H21/04 ; A61K48/00 ; A61K38/17 ; C07D213/80 ; A61K31/44 ; C07C229/66 ; A61K31/196 ; C07C331/30 ; A61K31/26 ; C07K7/18 ; A61P25/28 ; A61P25/08 ; A61P25/00 ; A61P25/32 ; B01L3/00 ; G01R27/28 ; C07H21/02
摘要：
A GABA (gamma-aminobutyric acid) release-inhibiting agent in the cerebellum and a composition for treating pathological symptoms caused by over-release of GABA in the cerebellum, each comprising a Bestrophin 1(Best1) channel inhibitor as an active ingredient; a GABA release-promoting agent in the cerebellum and a composition for treating pathological symptoms caused by the deficit of GABA in the cerebellum, each comprising a Best1 channel activator as an active ingredient; and a method for screening a GABA release-regulating agent in the cerebellum, which uses Best1 channel as target, are provided.
公开/授权文献
- US09095535B2 GABA release-regulating agent in cerebellum 公开/授权日：2015-08-04
信息查询
IPC分类:
