发明申请
US20120220599A1 AZA-BICYCLOALKYL ETHERS AND THEIR USE AS ALPHA7-NACHR AGONISTS
审中-公开
AZA-BICYCLOALKYL ETHERS及其作为ALPHA7-NACHR AGONISTS的用途
- 专利标题： AZA-BICYCLOALKYL ETHERS AND THEIR USE AS ALPHA7-NACHR AGONISTS
- 专利标题（中）： AZA-BICYCLOALKYL ETHERS及其作为ALPHA7-NACHR AGONISTS的用途
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申请号： US13462187申请日： 2012-05-02
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公开(公告)号： US20120220599A1公开(公告)日： 2012-08-30
- 发明人: Dominik FEUERBACH , Konstanze HURTH , Timothy John RITCHIE
- 申请人： Dominik FEUERBACH , Konstanze HURTH , Timothy John RITCHIE
- 专利权人： NOVARTIS AG
- 当前专利权人： NOVARTIS AG
- 优先权： GB220581.3 20020904
- 主分类号： A61K31/501
- IPC分类号： A61K31/501 ; A61K31/506 ; A61K31/4439 ; A61P25/28 ; A61P25/18 ; C07D487/08 ; C07D453/02 ; A61K31/439
摘要：
The present invention relates to 1-aza-bicycloalkyl derivatives of formula I, wherein X is CH2 or a single bond; Y is a group of formula and wherein R has the meanings as defined in the specification, which compounds are alpha 7 nicotinic acetylcholine receptor (nAChR) agonists; to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them.
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