发明申请
US20120220615A1 SUBSTITUTED INDOLYL ALKYL AMINO DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE
有权
取代的吲哚基氨基酸衍生物作为HISTONE脱乙酰基酶的新型抑制剂
- 专利标题: SUBSTITUTED INDOLYL ALKYL AMINO DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE
- 专利标题(中): 取代的吲哚基氨基酸衍生物作为HISTONE脱乙酰基酶的新型抑制剂
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申请号: US13447636申请日: 2012-04-16
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公开(公告)号: US20120220615A1公开(公告)日: 2012-08-30
- 发明人: Marc Gustaaf Celine Verdonck , Patrick René Angibaud , Bruno Roux , Isabelle Noëlle Constance Pilatte , Peter Ten Holte , Janine Arts , Kristof Van Emelen
- 申请人: Marc Gustaaf Celine Verdonck , Patrick René Angibaud , Bruno Roux , Isabelle Noëlle Constance Pilatte , Peter Ten Holte , Janine Arts , Kristof Van Emelen
- 优先权: EP04077172.7 20040728
- 主分类号: C07D401/14
- IPC分类号: C07D401/14 ; A61P35/04 ; C07D491/04 ; A61K31/506
摘要:
This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, X and Y have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
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