发明申请
- 专利标题： CHIMERIC ADENOVIRUSES FOR USE IN CANCER TREATMENT
- 专利标题（中）： 用于癌症治疗的CHIMERIC ADENOVIRUSES
-
申请号： US13443055申请日： 2012-04-10
-
公开(公告)号： US20120231524A1公开(公告)日： 2012-09-13
- 发明人: Paul HARDEN , Terry HERMISTON , Irene KUHN
- 申请人： Paul HARDEN , Terry HERMISTON , Irene KUHN
- 申请人地址： GB London
- 专利权人： PsiOxus Therapeutics Limited
- 当前专利权人： PsiOxus Therapeutics Limited
- 当前专利权人地址： GB London
- 主分类号： C12N7/01
- IPC分类号： C12N7/01
摘要：
The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
公开/授权文献
- US08765463B2 Chimeric adenoviruses for use in cancer treatment 公开/授权日：2014-07-01