发明申请
- 专利标题： Compositions and Methods for Treatment of Eye Disorders
- 专利标题（中）： 眼部疾病治疗的组合和方法
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申请号： US13398542申请日： 2012-02-16
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公开(公告)号： US20120232019A1公开(公告)日： 2012-09-13
- 发明人: Thomas Gadek , John Burnier , Johan Oslob , Wang Shen , Kenneth Barr , Min Zhong
- 申请人： Thomas Gadek , John Burnier , Johan Oslob , Wang Shen , Kenneth Barr , Min Zhong
- 申请人地址： US CA Brisbane
- 专利权人： SARcode Bioscience Inc.
- 当前专利权人： SARcode Bioscience Inc.
- 当前专利权人地址： US CA Brisbane
- 主分类号： A61K31/473
- IPC分类号： A61K31/473 ; A61K31/437 ; A61K31/197 ; A61K31/343 ; C07D409/14 ; A61K31/341 ; C07D405/14 ; C07D471/04 ; C07D409/12 ; A61K38/02 ; A61K31/4015
摘要：
The present invention provides compounds and methods for the treatment of LFA-1 mediated diseases. In particular, LFA-1 antagonists are described herein and these antagonists are used in the treatment of LFA-1 mediated diseases. One aspect of the invention provides for diagnosis of an LFA-1 mediated disease and administration of a LFA-1 antagonist, after the patient is diagnosed with a LFA-1 mediated disease. In some embodiments, the LFA-1 mediated diseases treated are dry eye disorders. Also provided herein are methods for identifying compounds which are LFA-1 antagonists.
公开/授权文献
- US08592450B2 Compositions and methods for treatment of eye disorders 公开/授权日：2013-11-26
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