发明申请
US20120232271A1 METHOD FOR PREPARATION OF OPTIONALLY 2-SUBSTITUTED 1,6-DIHYDRO-6-OXO-4-PYRIMIDINECARBOXYLIC ACIDS
审中-公开
选择性取代的2-取代的1,6-二羟基-6-氧代-4-吡啶羧酸的方法
- 专利标题： METHOD FOR PREPARATION OF OPTIONALLY 2-SUBSTITUTED 1,6-DIHYDRO-6-OXO-4-PYRIMIDINECARBOXYLIC ACIDS
- 专利标题（中）： 选择性取代的2-取代的1,6-二羟基-6-氧代-4-吡啶羧酸的方法
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申请号： US13477683申请日： 2012-05-22
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公开(公告)号： US20120232271A1公开(公告)日： 2012-09-13
- 发明人: RAFAEL SHAPIRO
- 申请人： RAFAEL SHAPIRO
- 申请人地址： US DE Wilmington
- 专利权人： E I DU PONT DE NEMOURS AND COMPANY
- 当前专利权人： E I DU PONT DE NEMOURS AND COMPANY
- 当前专利权人地址： US DE Wilmington
- 主分类号： C07D239/42
- IPC分类号： C07D239/42 ; C07D239/30 ; C07D239/34
摘要：
A new method for the preparation of optionally 2-substituted 1,6-dihydro-6-oxo-4-pyrimidinecarboxylic acid compounds of Formula 1 is disclosed wherein R1 is H or an optionally substituted carbon moiety. Also disclosed is the method comprising additional steps to prepare optionally substituted 4-pyrimidinecarboxylic acids and esters using the compound of Formula 1 as an intermediate.
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