A method to predict a distribution of material properties of a cast component. In one form, the method includes accepting at least one of dendrite arm spacing data and porosity data that have been previously determined, as well as accepting casting geometry data and structural analysis geometric data, calculating material properties of the casting based on one or both of dendrite arm spacing data and porosity data at each of the various nodes within the casting FEA or FD mesh and mapping the calculated material properties to the various nodes of the finished part FEA mesh. The method may be used as a basis for conducting fatigue or a related durability analysis on the component.