发明申请
US20120251493A1 NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION
审中-公开
HEPATITIS C病毒复制的新型MACROCYCLIC抑制剂
- 专利标题: NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION
- 专利标题(中): HEPATITIS C病毒复制的新型MACROCYCLIC抑制剂
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申请号: US13497740申请日: 2010-09-24
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公开(公告)号: US20120251493A1公开(公告)日: 2012-10-04
- 发明人: Scott D. Seiwert , John B. Nicholas , Brad Buckman , Vladimir Serebryany
- 申请人: Scott D. Seiwert , John B. Nicholas , Brad Buckman , Vladimir Serebryany
- 国际申请: PCT/US10/50284 WO 20100924
- 主分类号: A61K38/07
- IPC分类号: A61K38/07 ; C12N9/99 ; A61P1/16 ; A61K38/21 ; A61P31/14 ; C07K5/107 ; A61K38/05
摘要:
The embodiments provide compounds of the general Formula I, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.