Invention Application
US20120252025A1 METHODS FOR COVALENT LINKING OF OPTICAL REPORTERS 审中-公开
光学报告器共同连接方法

METHODS FOR COVALENT LINKING OF OPTICAL REPORTERS
Abstract:
A method to link a light emitting reporter to biomolecules with nucleotide oligomers is described. The light reporter particles are silylated and functionalized to produce a coated light reporter particle, prior to covalently linking the biomolecules to the light reporter particle. The light reporter particle generated by the methods of the invention can be excited by a light excitation source such as UV or IR light, and when the biomolecule is DNA, the attached DNA molecule(s) are detectable by amplification techniques such as PCR.
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