发明申请
- 专利标题: RNAi Modulation of APOB and Uses Thereof
- 专利标题(中): RNAi调节APOB及其用途
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申请号: US13450886申请日: 2012-04-19
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公开(公告)号: US20120252872A1公开(公告)日: 2012-10-04
- 发明人: Juergen Soutschek , Hans-Peter Vornlocher , Philipp Hadwiger , Sayda Elbashir
- 申请人: Juergen Soutschek , Hans-Peter Vornlocher , Philipp Hadwiger , Sayda Elbashir
- 申请人地址: US MA Cambridge
- 专利权人: ALNYLAM PHARMACEUTICALS, INC.
- 当前专利权人: ALNYLAM PHARMACEUTICALS, INC.
- 当前专利权人地址: US MA Cambridge
- 主分类号: A61K31/713
- IPC分类号: A61K31/713 ; A61P3/06 ; A61P9/10 ; A61P9/00 ; A61P7/02 ; C07H21/02 ; A61P3/00
摘要:
The invention relates to compositions and methods for modulating the expression of apolipoprotein B, and more particularly to the downregulation of apolipoprotein B by chemically modified oligonucleotides.
公开/授权文献
- US08592571B2 RNAi modulation of APOB and uses thereof 公开/授权日:2013-11-26
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