发明申请
- 专利标题: SUPPRESSORS OF CpG OLIGONUCLEOTIDES AND METHODS OF USE
- 专利标题(中): CpG寡核苷酸的抑制剂及其使用方法
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申请号: US13530028申请日: 2012-06-21
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公开(公告)号: US20120258144A1公开(公告)日: 2012-10-11
- 发明人: Dennis M. Klinman , Rainald Zeuner , Mayda Gursel , Ihsan Gursel , Daniela Verthelyi
- 申请人: Dennis M. Klinman , Rainald Zeuner , Mayda Gursel , Ihsan Gursel , Daniela Verthelyi
- 专利权人: Department of Health and Human Services.,The Government of the United States of America as represented by the Secretary of the
- 当前专利权人: Department of Health and Human Services.,The Government of the United States of America as represented by the Secretary of the
- 主分类号: A61K31/7088
- IPC分类号: A61K31/7088 ; A61P37/06 ; C07H21/04
摘要:
The present disclosure relates to oligodeoxynucleotides that suppress an immune response. Methods are disclosed for preventing or treating an immune-mediated disorder, such as, but not limited to, an autoimmune disease, by administering a therapeutically effective amount of a suppressive oligodeoxynucleotide. Also disclosed are methods of suppressing an immune response in a subject by administering a therapeutically effective amount of a suppressive oligodeoxynucleotide.
公开/授权文献
- US08580944B2 Suppressors of CpG oligonucleotides and methods of use 公开/授权日:2013-11-12
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