发明申请
- 专利标题: ADAMANTYL COMPOUNDS
- 专利标题(中): ADAMANTYL化合物
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申请号: US13437984申请日: 2012-04-03
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公开(公告)号: US20120258982A1公开(公告)日: 2012-10-11
- 发明人: Adrian Wai-Hing Cheung , Kevin Richard Guertin , Nancy-Ellen Haynes , Eric Mertz , Lida Qi , Yimin Qian , Nathan Robert Scott
- 申请人: Adrian Wai-Hing Cheung , Kevin Richard Guertin , Nancy-Ellen Haynes , Eric Mertz , Lida Qi , Yimin Qian , Nathan Robert Scott
- 主分类号: A61K31/4375
- IPC分类号: A61K31/4375 ; C07D215/233 ; A61K31/47 ; A61P19/02 ; A61P11/06 ; A61P13/12 ; A61P25/28 ; A61P25/16 ; A61P9/10 ; A61P35/00 ; A61P35/02 ; C07D471/04 ; A61P3/10
摘要:
The invention relates to JNK inhibitors and corresponding methods, formulations, and compositions for inhibiting JNK and treating JNK-mediated disorders. The application discloses JNK inhibitors, as described below in Formula I: wherein the variables are as defined herein. The compounds and compositions disclosed herein are useful to modulate the activity of JNK and treat diseases associated with JNK activity. Disclosed are methods and formulations for inhibiting JNK and treating JNK-mediated disorders, and the like, with the compounds, and processes for making said compounds, and corresponding compositions, disclosed herein.
公开/授权文献
- US08471027B2 Adamantyl compounds 公开/授权日:2013-06-25
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