发明申请
US20120264704A1 SUBSTITUTED DIHYDROPYRAZOLONES AND USE THEREOF AS HIF-PROLYL-4 -HYDROXYLASE INHIBITORS
有权
取代的二氢吡咯烷酮及其作为HIF-PROLYL-4-羟基酶抑制剂的用途
- 专利标题： SUBSTITUTED DIHYDROPYRAZOLONES AND USE THEREOF AS HIF-PROLYL-4 -HYDROXYLASE INHIBITORS
- 专利标题（中）： 取代的二氢吡咯烷酮及其作为HIF-PROLYL-4-羟基酶抑制剂的用途
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申请号： US12447201申请日： 2007-10-26
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公开(公告)号： US20120264704A1公开(公告)日： 2012-10-18
- 发明人: Kai Thede , Ingo Flamme , Felix Oehme , Jens-Kerim Ergüden , Friederike Stoll , Joachim Schuhmacher , Hanno Wild , Peter Kolkhof , Hartmut Beck , Metin Akbaba , Mario Jeske
- 申请人： Kai Thede , Ingo Flamme , Felix Oehme , Jens-Kerim Ergüden , Friederike Stoll , Joachim Schuhmacher , Hanno Wild , Peter Kolkhof , Hartmut Beck , Metin Akbaba , Mario Jeske
- 优先权： DE10-2006-050-519.1 20061026
- 国际申请： PCT/EP07/08977 WO 20071026
- 主分类号： A61K31/506
- IPC分类号： A61K31/506 ; C07D417/14 ; A61K31/4439 ; C07D413/14 ; A61K31/5377 ; A61K31/517 ; A61K31/501 ; A61K31/4709 ; A61K31/497 ; A61K31/55 ; A61P7/10 ; A61K31/616 ; A61P31/04 ; A61P35/00 ; A61K31/7048 ; A61P9/00 ; A61P7/06 ; A61P13/12 ; C07D471/04 ; A61K31/498 ; A61K31/714 ; C07D401/14
摘要：
The present application relates to novel substituted dihydropyrazolone derivatives, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and hematological diseases and kidney diseases, and for promoting wound healing.