发明申请
US20120264967A1 PROCESS FOR MAKING (R) -3-(2,3-DIHYDROXYPROPYL)-6-FLUORO-5-(2-FLOURO-4-IODOPHENYLAMINO)-8-METHYLPYRIDO[2,3-d]PYRIMIDINE-4,7(3H,8H)-DIONE AND INTERMEDIATES THEREOF
有权
制备（R）-3-（2,3-二羟基丙基）-6-氟-5-（2-氟-4-碘杂亚氨基）-8-甲基吡啶并[2,3-d]嘧啶-4,7（3H ，8H） - 其和其中间体
![PROCESS FOR MAKING (R) -3-(2,3-DIHYDROXYPROPYL)-6-FLUORO-5-(2-FLOURO-4-IODOPHENYLAMINO)-8-METHYLPYRIDO[2,3-d]PYRIMIDINE-4,7(3H,8H)-DIONE AND INTERMEDIATES THEREOF](/docs/US/2012-10-18/US20120264967A1/abs.jpg.600x600.jpg)
- 专利标题： PROCESS FOR MAKING (R) -3-(2,3-DIHYDROXYPROPYL)-6-FLUORO-5-(2-FLOURO-4-IODOPHENYLAMINO)-8-METHYLPYRIDO[2,3-d]PYRIMIDINE-4,7(3H,8H)-DIONE AND INTERMEDIATES THEREOF
- 专利标题（中）： 制备（R）-3-（2,3-二羟基丙基）-6-氟-5-（2-氟-4-碘杂亚氨基）-8-甲基吡啶并[2,3-d]嘧啶-4,7（3H ，8H） - 其和其中间体
-
申请号： US13421421申请日： 2012-03-15
-
公开(公告)号： US20120264967A1公开(公告)日： 2012-10-18
- 发明人: David Paul Provencal , Todd Miller , Yuxin Zhao , Jonathon S. Salsbury
- 申请人： David Paul Provencal , Todd Miller , Yuxin Zhao , Jonathon S. Salsbury
- 申请人地址： JP Osaka
- 专利权人： TAKEDA PHARMACEUTICAL COMPANY LIMITED
- 当前专利权人： TAKEDA PHARMACEUTICAL COMPANY LIMITED
- 当前专利权人地址： JP Osaka
- 主分类号： C07C255/23
- IPC分类号： C07C255/23
![PROCESS FOR MAKING (R) -3-(2,3-DIHYDROXYPROPYL)-6-FLUORO-5-(2-FLOURO-4-IODOPHENYLAMINO)-8-METHYLPYRIDO[2,3-d]PYRIMIDINE-4,7(3H,8H)-DIONE AND INTERMEDIATES THEREOF](/abs-image/US/2012/10/18/US20120264967A1/abs.jpg.150x150.jpg)
摘要：
The present invention relates generally to processes of making (R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione, intermediates thereof, and a process for making a particular polymorph of (R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione.
公开/授权文献
信息查询
