发明申请
- 专利标题: FLUORINATED DERIVATES OF 3-HYDROXYPYRIDIN-4-ONES
- 专利标题(中): 3-羟基吡啶-4-酮的氟化衍生物
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申请号: US13382130申请日: 2010-07-05
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公开(公告)号: US20120270882A1公开(公告)日: 2012-10-25
- 发明人: Tim Fat Tam , Regis Leung-Toung , Yingsheng Wang , Yangqing Zhao , Tao Xin , Birenkumar Shah , Blaise N'zemba , Jolanta Maria Wodzinska , Maryna Premyslova
- 申请人: Tim Fat Tam , Regis Leung-Toung , Yingsheng Wang , Yangqing Zhao , Tao Xin , Birenkumar Shah , Blaise N'zemba , Jolanta Maria Wodzinska , Maryna Premyslova
- 申请人地址: CA Toronto
- 专利权人: APOTEX TECHNOLOGIES INC.
- 当前专利权人: APOTEX TECHNOLOGIES INC.
- 当前专利权人地址: CA Toronto
- 国际申请: PCT/CA2010/001027 WO 20100705
- 主分类号: C07D213/69
- IPC分类号: C07D213/69 ; A61P35/00 ; A61K31/496 ; C07D401/06 ; A61K31/4545 ; A61K31/4412 ; A61P13/12
摘要:
Provided are compounds of Formula I which are derivatives of 3-Hydroxypyridin-4-ones. The compounds may be used in treatment of a medical condition related to a toxic concentration of iron. The compounds may be used for preparation of a medicament for treatment of a medical condition related to a toxic concentration of iron. The medical condition related to a toxic concentration of iron may be selected from the group consisting of: cancer, pulmonary disease, progressive kidney disease and Frederich's Ataxia.
公开/授权文献
- US09073865B2 Fluorinated derivates of 3-hydroxypyridin-4-ones 公开/授权日:2015-07-07
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