发明申请
- 专利标题: RADIOPAQUE INJECTABLE NUCLEUS HYDROGEL COMPOSITIONS
- 专利标题(中): 放射性注射核糖核酸组合物
-
申请号: US13094512申请日: 2011-04-26
-
公开(公告)号: US20120276008A1公开(公告)日: 2012-11-01
- 发明人: Jared W. Walkenhorst , Keith A. Collins , Dennis Y. Lee , Thomas G. Wilson , Thomas J. Douville , Ulrich Berlemann
- 申请人: Jared W. Walkenhorst , Keith A. Collins , Dennis Y. Lee , Thomas G. Wilson , Thomas J. Douville , Ulrich Berlemann
- 申请人地址: US CT Shelton
- 专利权人: SPINE WAVE, INC.
- 当前专利权人: SPINE WAVE, INC.
- 当前专利权人地址: US CT Shelton
- 主分类号: A61K49/00
- IPC分类号: A61K49/00
摘要:
In one embodiment, the invention relates to a composition suitable for preparing a hydrogel useful as replacement material for all or part of a disc nucleus. The composition comprises: a curable, cross-linkable, non-immunogenic, non-toxic protein comprising a minimum of about 10% and a maximum of about 25% of the hydrogel by weight; a metal contrast agent comprising a minimum of about 2% and a maximum of about 70% of the hydrogel by weight; and a crosslinker comprising a minimum of about 0.1% and a maximum of about 10% of the hydrogel by weight; wherein the composition has a discernable radiopacity level.
信息查询