发明申请
- 专利标题: METHODS OF TREATING CANCER USING IL-21
- 专利标题(中): 使用IL-21治疗癌症的方法
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申请号: US13535832申请日: 2012-06-28
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公开(公告)号: US20120294798A1公开(公告)日: 2012-11-22
- 发明人: Andrew J. Nelson , Steven D. Hughes , Richard D. Holly
- 申请人: Andrew J. Nelson , Steven D. Hughes , Richard D. Holly
- 专利权人: ZymoGenetics, Inc.
- 当前专利权人: ZymoGenetics, Inc.
- 主分类号: A61K38/20
- IPC分类号: A61K38/20 ; A61P35/02 ; A61K51/08 ; A61N5/00 ; A61K38/21 ; A61P37/04 ; A61K39/00 ; A61K39/395 ; A61P35/00 ; A61P37/02
摘要:
Methods for treating mammals with cancer using molecules that have an IL-21 functional activity are described. The molecules having IL-21 functional activities include polypeptides that have homology to the human IL-21 polypeptide sequence and proteins fused to a polypeptide with IL-21 functional activity. The molecules can be used as a monotherapy or in combination with other known cancer therapeutics.
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