发明申请
US20120295988A1 Pharmaceutical Compositions of Dispersions of Amorphous Drugs Mixed with Polymers
有权
与聚合物混合的无定形药物分散体的药物组合物
- 专利标题： Pharmaceutical Compositions of Dispersions of Amorphous Drugs Mixed with Polymers
- 专利标题（中）： 与聚合物混合的无定形药物分散体的药物组合物
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申请号： US13563536申请日： 2012-07-31
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公开(公告)号： US20120295988A1公开(公告)日： 2012-11-22
- 发明人: Walter C. Babcock , William J. Curatolo , Dwayne T. Friesen , Rodney J. Ketner , Julian B. Lo , James A. S. Nightingale , Ravi M. Shanker , James B. West
- 申请人： Walter C. Babcock , William J. Curatolo , Dwayne T. Friesen , Rodney J. Ketner , Julian B. Lo , James A. S. Nightingale , Ravi M. Shanker , James B. West
- 主分类号： A61K47/38
- IPC分类号： A61K47/38 ; A61P25/22 ; A61P7/02 ; A61P25/08 ; A61P25/28 ; A61P35/00 ; A61P29/00 ; A61P25/18 ; A61P3/04 ; A61P31/04 ; A61P9/12 ; A61P11/14
摘要：
A pharmaceutical composition comprises a dispersion comprising a low-solubility drug and a matrix combined with a concentration-enhancing polymer. At least a major portion of the drug is amorphous in the dispersion. The compositions improve the stability of the drug in the dispersion, and/or the concentration of drug in a use environment.
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