发明申请
![DERIVATIVES OF PYRIMIDO [6,1-A] ISOQUINOLIN-4-ONE](/docs/US/2012-11-29/US20120302533A1/abs.jpg.600x600.jpg)
- 专利标题： DERIVATIVES OF PYRIMIDO [6,1-A] ISOQUINOLIN-4-ONE
- 专利标题（中）： 吡咯烷[6,1-A]异喹啉-4-酮的衍生物
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申请号： US13568754申请日： 2012-08-07
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公开(公告)号： US20120302533A1公开(公告)日： 2012-11-29
- 发明人: Alexander William Oxford , David Jack
- 申请人： Alexander William Oxford , David Jack
- 申请人地址： GB London
- 专利权人： Verona Pharma plc
- 当前专利权人： Verona Pharma plc
- 当前专利权人地址： GB London
- 优先权： GBGB9907454.4 19990331; GBGB9909802.2 19990428
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; A61P11/08 ; A61P29/00 ; A61K31/56
![DERIVATIVES OF PYRIMIDO [6,1-A] ISOQUINOLIN-4-ONE](/abs-image/US/2012/11/29/US20120302533A1/abs.jpg.150x150.jpg)
摘要：
The present invention relates to derivatives of pyrimido[6,1-a]isoquinolin-4-one and their application as inhibitors of phosphodiesterase (PDE) isoenzymes. More particularly the invention relates to derivatives of pyrimido[6,1-a]isoquinolin-4-one and their use in medicine for example as bronchodilators with anti-inflammatory properties.