发明申请
US20120308584A1 PROTEIN-ACTIVE AGENT CONJUGATES AND METHOD FOR PREPARING THE SAME
审中-公开
蛋白活性物质结合物及其制备方法
- 专利标题： PROTEIN-ACTIVE AGENT CONJUGATES AND METHOD FOR PREPARING THE SAME
- 专利标题（中）： 蛋白活性物质结合物及其制备方法
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申请号： US13466875申请日： 2012-05-08
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公开(公告)号： US20120308584A1公开(公告)日： 2012-12-06
- 发明人: Yongzu Kim , Taekyo Park , Sungho Woo , Hyangsook Lee , Sunyoung Kim , Jongun Cho , Doohwan Jung , Youngun Kim , Hyunjin Kwon , Kyuman Oh , Yunseo Chung , Yun-Hee Park
- 申请人： Yongzu Kim , Taekyo Park , Sungho Woo , Hyangsook Lee , Sunyoung Kim , Jongun Cho , Doohwan Jung , Youngun Kim , Hyunjin Kwon , Kyuman Oh , Yunseo Chung , Yun-Hee Park
- 申请人地址： KR Daejeon
- 专利权人： LEGOCHEM BIOSCIENCES, INC.
- 当前专利权人： LEGOCHEM BIOSCIENCES, INC.
- 当前专利权人地址： KR Daejeon
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/00 ; C12P21/00
摘要：
The invention provides protein-active agent conjugates having an amino acid motif that can be recognized by an isoprenoid transferase. The invention also provides compositions containing the conjugates, as well as methods for making the conjugates and compositions. The invention further provides methods for using the conjugates to deliver the active agent to a target cell, as well as methods for using the conjugates to treat a subject in need thereof (e.g., a subject in need of the active agent).
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