Invention Application
- Patent Title: CYTOCHROME P450 OXIDASE INHIBITORS AND USES THEREOF
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Application No.: US13587516Application Date: 2012-08-16
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Publication No.: US20120309762A1Publication Date: 2012-12-06
- Inventor: Larry L. Klein , Hui-Ju Chen , Ming C. Yeung , Charles A. Flentge , John T. Randolph , Peggy P. Huang , Douglas K. Hutchinson , Dale J. Kempf
- Applicant: Larry L. Klein , Hui-Ju Chen , Ming C. Yeung , Charles A. Flentge , John T. Randolph , Peggy P. Huang , Douglas K. Hutchinson , Dale J. Kempf
- Applicant Address: US IL Abbott Park
- Assignee: Abbott Laboratories
- Current Assignee: Abbott Laboratories
- Current Assignee Address: US IL Abbott Park
- Main IPC: C07D277/24
- IPC: C07D277/24 ; C07D417/12 ; A61K31/4439 ; A61K31/426 ; A61K31/427 ; A61P31/12 ; C07D417/14 ; A61K31/5355 ; A61K31/496 ; A61K31/5377 ; A61K31/454 ; C12N9/99 ; A61K31/513
Abstract:
The present invention features compounds of formula I or pharmaceutically acceptable salts, solvates or prodrugs thereof, and methods of using the same to inhibit the metabolizing activities of CYP enzymes. The present invention also features methods of using these compounds, salts, solvates or prodrugs to improve the pharmacokinetics of drugs that are metabolized by CYP enzymes.
Information query
