发明申请
- 专利标题: Methods of Detecting Target Nucleic Acids
- 专利标题(中): 检测靶核酸的方法
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申请号: US13590794申请日: 2012-08-21
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公开(公告)号: US20120316083A1公开(公告)日: 2012-12-13
- 发明人: Muhammad A. Sharaf , Timothy M. Woudenberg , Khairuzzaman Bashar Mullah
- 申请人: Muhammad A. Sharaf , Timothy M. Woudenberg , Khairuzzaman Bashar Mullah
- 申请人地址: US CA Carlsbad
- 专利权人: LIFE TECHNOLOGIES CORPORATION
- 当前专利权人: LIFE TECHNOLOGIES CORPORATION
- 当前专利权人地址: US CA Carlsbad
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C40B30/04 ; G01N33/53
摘要:
The present disclosure relates to methods of identifying target nucleic acids by using coded molecules and its analysis by translocation through a nanopore. Generally, coded molecules are subject to a target polynucleotide dependent modification. The modified coded molecule is detected by isolating the modified coded molecules from the unmodified coded molecules prior to analysis through the nanopore or by detecting a change in the signal pattern of the coded molecule when analyzed through the nanopore.
公开/授权文献
- US08637247B2 Methods of detecting target nucleic acids 公开/授权日:2014-01-28
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