发明申请
- 专利标题： SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF
- 专利标题（中）： 选择性糖苷酶抑制剂及其用途
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申请号： US13591927申请日： 2012-08-22
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公开(公告)号： US20120316207A1公开(公告)日： 2012-12-13
- 发明人: David Vocadlo , Ernest McEachern , Keith Stubbs , Tong-Shuang Li , Garrett Whitworth , Julia Heinonen , Matthew Macauley
- 申请人： David Vocadlo , Ernest McEachern , Keith Stubbs , Tong-Shuang Li , Garrett Whitworth , Julia Heinonen , Matthew Macauley
- 申请人地址： CA Burnaby
- 专利权人： Simon Fraser University
- 当前专利权人： Simon Fraser University
- 当前专利权人地址： CA Burnaby
- 主分类号： A61K31/429
- IPC分类号： A61K31/429 ; C07D513/04
摘要：
The invention provides compounds of formula (I) for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-GlcNAc.
公开/授权文献
- US08962664B2 Selective glycosidase inhibitors and uses thereof 公开/授权日：2015-02-24
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IPC分类:
