Invention Application
- Patent Title: METHODS OF REDUCING VIRULENCE IN BACTERIA
- Patent Title (中): 减少细菌中毒性的方法
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Application No.: US13579373Application Date: 2011-02-16
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Publication No.: US20120322769A1Publication Date: 2012-12-20
- Inventor: Ching-Hong Yang , Xin Chen , Eric J. Toone
- Applicant: Ching-Hong Yang , Xin Chen , Eric J. Toone
- Applicant Address: US NC Durham US WI Milwaukee
- Assignee: DUKE UNIVERSITY,UWM RESEARCH FOUNDATION
- Current Assignee: DUKE UNIVERSITY,UWM RESEARCH FOUNDATION
- Current Assignee Address: US NC Durham US WI Milwaukee
- International Application: PCT/US11/25082 WO 20110216
- Main IPC: C12N1/36
- IPC: C12N1/36 ; A61P31/04 ; A01P1/00 ; A01N37/10 ; C07C57/30 ; C07C57/38 ; C07D333/24 ; A61K31/381 ; A01N43/10 ; C07D209/18 ; A61K31/405 ; A01N43/38 ; C07D213/55 ; A61K31/435 ; A01N43/40 ; C07D233/64 ; A61K31/4172 ; A01N43/50 ; C07C59/13 ; C07C235/42 ; A61K31/165 ; A01N37/18 ; C07F9/40 ; A61K31/662 ; A01N57/22 ; A61K31/192

Abstract:
A method of reducing virulence in a bacterium comprising at least one of a GacS/GacA-type system, a HrpX/HrpY-type system, a T3SS-type system, and a Rsm-type system, the method comprising contacting the bacterium with an effective amount of a compound described herein.
Public/Granted literature
- US09260382B2 Methods of reducing virulence in bacteria Public/Granted day:2016-02-16
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