发明申请
US20130005983A1 METHOD FOR PRODUCING 3-HALO-1,2-BENZISOTHIAZOLES
有权
3-HALO-1,2-BENZISOTHIAZOLES的生产方法
- 专利标题: METHOD FOR PRODUCING 3-HALO-1,2-BENZISOTHIAZOLES
- 专利标题(中): 3-HALO-1,2-BENZISOTHIAZOLES的生产方法
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申请号: US13634450申请日: 2011-03-14
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公开(公告)号: US20130005983A1公开(公告)日: 2013-01-03
- 发明人: Shigeki Sakaue , Sachio Iida
- 申请人: Shigeki Sakaue , Sachio Iida
- 申请人地址: JP Kako-gun
- 专利权人: SUMITOMO SEIKA CHEMICALS CO., LTD.
- 当前专利权人: SUMITOMO SEIKA CHEMICALS CO., LTD.
- 当前专利权人地址: JP Kako-gun
- 优先权: JP2010-086377 20100402
- 国际申请: PCT/JP2011/055943 WO 20110314
- 主分类号: C07D275/04
- IPC分类号: C07D275/04
摘要:
A method for producing a 3-halo-1,2-benzisothiazole represented by the general formula (2): wherein R1 is a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms, an alkoxycarbonyl group having 2 to 5 carbon atoms, a nitro group or a halogen atom, and X is a halogen atom, the method characterized by reacting a 1,2-benzisothiazol-3-one represented by the general formula (1): wherein R1 is the same group as the R1 defined in the above general formula (2), with a thionyl halide in a polar solvent. The 3-halo-1,2-benzisothiazole obtainable according to the method of the present invention is suitably used as production raw materials and the like for a medicament and the like.
公开/授权文献
- US08664404B2 Method for producing 3-halo-1,2-benzisothiazoles 公开/授权日:2014-03-04
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