发明申请
- 专利标题: HETEROCYCLIC INHIBITORS OF MEK AND METHODS OF USE THEREOF
- 专利标题(中): MEK的杂环抑制剂及其使用方法
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申请号: US13614711申请日: 2012-09-13
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公开(公告)号: US20130018075A1公开(公告)日: 2013-01-17
- 发明人: Allison L. Marlow , Eli Wallace , Jeongbeob Seo , Joseph P. Lyssikatos , Hong Woon Yang , James Blake
- 申请人: Allison L. Marlow , Eli Wallace , Jeongbeob Seo , Joseph P. Lyssikatos , Hong Woon Yang , James Blake
- 主分类号: A61K31/4412
- IPC分类号: A61K31/4412 ; A61P35/00
摘要:
Disclosed are methods of treating hyperproliferative disorders, method of treating inflammatory disorders, and methods of inhibiting MEK activity in a mammal, comprising administering an effective amount of one or more compounds of the Formula V or pharmaceutically acceptable salts thereof, wherein R1, R2, R7, R8, R9 and W are as defined in the specification.
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