发明申请
- 专利标题： iRNA Agents Targeting VEGF
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申请号： US13620212申请日： 2012-09-14
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公开(公告)号： US20130018085A1公开(公告)日： 2013-01-17
- 发明人: Antonin de Fougerolles , Maria Frank-Kamenetsky , Muthiah Manoharan , Kallanthottathil G. Rajeev , Philipp Hadwiger
- 申请人： Antonin de Fougerolles , Maria Frank-Kamenetsky , Muthiah Manoharan , Kallanthottathil G. Rajeev , Philipp Hadwiger
- 主分类号： A61K31/713
- IPC分类号： A61K31/713 ; A61P35/00 ; A61P27/02 ; C12N5/071 ; C07H21/02
摘要：
The features of the present invention relate to compounds, compositions and methods useful for modulating the expression of vascular endothelial growth factor (VEGF), such as by the mechanism of RNA interference (RNAi). The compounds and compositions include iRNA agents that can be unmodified or chemically-modified.
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