发明申请
US20130022975A1 METHOD FOR DETECTING ARTERIOSCLEROTIC DISEASES ON THE BASIS OF SINGLE NUCLEOTIDE POLYMORPHISM AT HUMAN CHROMOSOME 5P15.3
审中-公开
在人类色素5P15.3单核细胞多态性基础上检测异常性疾病的方法
- 专利标题: METHOD FOR DETECTING ARTERIOSCLEROTIC DISEASES ON THE BASIS OF SINGLE NUCLEOTIDE POLYMORPHISM AT HUMAN CHROMOSOME 5P15.3
- 专利标题(中): 在人类色素5P15.3单核细胞多态性基础上检测异常性疾病的方法
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申请号: US13579463申请日: 2011-02-18
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公开(公告)号: US20130022975A1公开(公告)日: 2013-01-24
- 发明人: Kouichi Ozaki , Toshihiro Tanaka , Yusuke Nakamura
- 申请人: Kouichi Ozaki , Toshihiro Tanaka , Yusuke Nakamura
- 申请人地址: JP Saitama
- 专利权人: RIKEN
- 当前专利权人: RIKEN
- 当前专利权人地址: JP Saitama
- 优先权: JP2010-033913 20100218
- 国际申请: PCT/JP2011/053542 WO 20110218
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C07H21/04
摘要:
An atherosclerotic disease such as myocardial infarction or angina pectoris is detected by analyzing a single nucleotide polymorphism on human chromosome 5p15.3, and by associating results of the analysis with the risk of the onset thereof. Examples of the single nucleotide polymorphism on human chromosome 5p15.3 include a nucleotide corresponding to the nucleotide at position 61 in the nucleotide sequence of SEQ ID NO: 1, SEQ ID NO: 2, or SEQ ID NO: 3, and a polymorphism at a nucleotide which is in linkage disequilibrium with the above nucleotide.
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