- 专利标题： ETHANOL PRODUCTIVITIES OF SACCHAROMYCES CEREVISIAE STRAINS IN FERMENTATION OF DILUTE-ACID HYDROLYZATES DEPEND ON THEIR FURAN REDUCTION CAPACITIES
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申请号： US13545343申请日： 2012-07-10
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公开(公告)号： US20130023022A1公开(公告)日： 2013-01-24
- 发明人: Anneli Nilsson , Gunnar Lidén , Marie-Francoise Gorwa-Grauslund , Barbel Hahn-Hägerdal , Carl Tobias Modig , Joao Ricardo Moreira De Almeida
- 申请人： Anneli Nilsson , Gunnar Lidén , Marie-Francoise Gorwa-Grauslund , Barbel Hahn-Hägerdal , Carl Tobias Modig , Joao Ricardo Moreira De Almeida
- 申请人地址： SE Lund
- 专利权人： SCANDINAVIAN TECHNOLOGY GROUP AB
- 当前专利权人： SCANDINAVIAN TECHNOLOGY GROUP AB
- 当前专利权人地址： SE Lund
- 优先权： SE0401303-3 20040519
- 主分类号： C12N1/19
- IPC分类号： C12N1/19 ; C12P7/10
摘要：
The present invention relates to an ethanol producing microbial strain, such as Saccharomyces cerevisiae strain, being able to grow and produce ethanol from lignocellulosic hydrolysates comprising growth inhibiting compounds of the group furfural and 5-hydroxy-methyl furfural, in a batch, fed-batch or continuous fermentation, said microbial strain being tolerant to such inhibiting compounds, which strain is upregulated and/or over expressed with regard to one or more of the following genes: LAT1, ALD6, ADH5, ADH6, GDH3, OYE3, SER3, GND2, MDH2, IDP3, ADH7, AAD15, ERG27, HMG1, LYS5, SPS19, SGE1.
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