A device for operating a drive unit generates setpoint values for controlling the drive unit based on, for example driver-generated input parameters. The device generates a first setpoint value for a front-axle drive and a second setpoint value for a rear-axle drive and includes a load impact damping unit which, in the event of a risk of load impacts, processes the setpoint values so as to damp the load impacts. The load impact damping unit is divided into a first load impact damping filter for processing the first setpoint value for the front axle drive and into a second load impact damping filter for processing the second setpoint value for the rear axle drive, and supplies corresponding filtered setpoint values to these drives.