发明申请
US20130046118A1 METHOD FOR PRODUCING OPTICALLY ACTIVE, RACEMIC MENTHOL 审中-公开
用于生产光学活性的,法定的MENTHOL的方法

METHOD FOR PRODUCING OPTICALLY ACTIVE, RACEMIC MENTHOL
摘要:
The present invention relates to a particularly economic overall method for producing menthol, specifically for producing optically active, essentially enantiomerically and diastereomerically pure L-menthol and racemic menthol, starting from the starting material citral which is available inexpensively on an industrial scale. The method comprises the following steps a.1) catalytic hydrogenation of neral and/or geranial to give citronellal, b.1) cyclization of citronellal to isopulegol in the presence of an acidic catalyst, c.1) purification of isopulegol by crystallization and d.1) catalytic hydrogenation of isopulegol to give menthol.
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