Invention Application
- Patent Title: PROCESSES FOR PREPARING SUBSTITUTED PYRIMIDINES
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Application No.: US13585861Application Date: 2012-08-15
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Publication No.: US20130066069A1Publication Date: 2013-03-14
- Inventor: Jean-Damien Charrier , Francesca Mazzei , David Kay , Andrew Miller
- Applicant: Jean-Damien Charrier , Francesca Mazzei , David Kay , Andrew Miller
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Cambridge
- Priority: USPCT/US2003/019266 20030619
- Main IPC: C07D403/14
- IPC: C07D403/14 ; C07D403/04 ; C07D403/12 ; C07D417/14 ; C07D453/02 ; C07D239/38 ; C07D413/14 ; C07D401/14
Abstract:
The present invention provides a facile process for the preparation of tri- and tetra-substituted pyrimidines. The process is useful for preparing inhibitors of protein kinases, especially Aurora kinase. These inhibitors are useful for treating or lessening the severity of Aurora-mediated diseases or conditions.
Public/Granted literature
- US08779127B2 Processes for preparing substituted pyrimidines Public/Granted day:2014-07-15
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