发明申请
- 专利标题: SOLUBLE GUANYLATE CYCLASE ACTIVATORS
- 专利标题(中): 可溶性冠状动脉激素
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申请号: US13699046申请日: 2011-05-24
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公开(公告)号: US20130072492A1公开(公告)日: 2013-03-21
- 发明人: Subharekha Raghavan , John E. Stelmach , Cameron J. Smith , Hong Li , Alan Whitehead , Sherman T. Waddell , Yi-Heng Chen , Shouwu Miao , Olga A. Ornoski , Joie Garfunkle , Xibin Liao , Jiang Chang , Xiaoqing Han , Jian Guo , Jonathan A. Groeper , Linda L. Brockunier , Keith Rosauer , Emma R. Parmee
- 申请人: Subharekha Raghavan , John E. Stelmach , Cameron J. Smith , Hong Li , Alan Whitehead , Sherman T. Waddell , Yi-Heng Chen , Shouwu Miao , Olga A. Ornoski , Joie Garfunkle , Xibin Liao , Jiang Chang , Xiaoqing Han , Jian Guo , Jonathan A. Groeper , Linda L. Brockunier , Keith Rosauer , Emma R. Parmee
- 国际申请: PCT/US11/37718 WO 20110524
- 主分类号: C07D487/04
- IPC分类号: C07D487/04 ; C07D495/04 ; A61K31/5025 ; A61P9/00 ; A61P9/10 ; A61P9/12 ; A61P9/04 ; A61P7/02 ; A61P15/00 ; A61P11/06 ; A61P13/12 ; A61P3/10 ; A61P1/16 ; A61P9/08 ; A61P3/00 ; A61P3/06 ; A61P7/10 ; A61K31/519
摘要:
A compound of Formula (I): or a pharmaceutically acceptable salt thereof, are capable of modulating the body's production of cyclic guanosine monophosphate (“cGMP”) and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The invention furthermore relates to processes for preparing compounds of Formula I, or a pharmaceutically acceptable salt thereof, for their use in the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical preparations which comprise compounds of Formula (I) or a pharmaceutically acceptable salt thereof.
公开/授权文献
- US09365574B2 Soluble guanylate cyclase activators 公开/授权日:2016-06-14
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