Invention Application
US20130078720A1 METHOD FOR INDUCING PLURIPOTENCY IN HUMAN SOMATIC CELLS WITH PRDM14 OR NFRKB
有权
用PRDM14或NFRKB在人类皮肤细胞中诱导人肺腺癌的方法
- Patent Title: METHOD FOR INDUCING PLURIPOTENCY IN HUMAN SOMATIC CELLS WITH PRDM14 OR NFRKB
- Patent Title (中): 用PRDM14或NFRKB在人类皮肤细胞中诱导人肺腺癌的方法
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Application No.: US13701437Application Date: 2011-06-02
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Publication No.: US20130078720A1Publication Date: 2013-03-28
- Inventor: Huck Hui Ng , Na Yu Chia , Bo Feng
- Applicant: Huck Hui Ng , Na Yu Chia , Bo Feng
- Applicant Address: SG Connexis
- Assignee: Agency for Science, Technology and Research
- Current Assignee: Agency for Science, Technology and Research
- Current Assignee Address: SG Connexis
- International Application: PCT/SG2011/000202 WO 20110602
- Main IPC: C12N5/071
- IPC: C12N5/071
Abstract:
Methods of inducing pluripotency in human somatic cells and methods of maintaining pluripotency in human embryonic stem cells (hESCs) are provided, as well as cells and uses of employing such cells. The methods comprise culturing cells in the presence of (i) OCT4 and SOX2; (ii) at least one of KLF4 and c-MYC; and at least one of PRDM14 and NFRKB.
Public/Granted literature
- US09234180B2 Method for inducing pluripotency in human somatic cells with PRDM14 or NFRKB Public/Granted day:2016-01-12
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