发明申请
US20130085461A1 Method for Pre-Debriding Treatment of Non-Viable Skin Tissue and Compositions and System Thereof 审中-公开
预先治疗非活动性皮肤组织及其组合物及其系统的方法

Method for Pre-Debriding Treatment of Non-Viable Skin Tissue and Compositions and System Thereof
摘要:
A pre-debriding composition comprises a chaotropic agent, preferably urea, and, preferably, exfoliating and analgesic agents. The pre-debriding composition reduces the collagen denaturation temperature, Tm, at the site of a wound. Use of the composition along with a supply of heat increases the effectiveness of a subsequent enzymatic debriding treatment. A dressing and heating system is also provided for use with the pre-debriding composition. An “instant activated” debriding composition and package is provided comprising a gel composition and a powdered debriding zymogen composition, wherein mixing of the two compositions results in an activated enzymatic debriding composition. 22290368.1
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