发明申请
US20130089558A1 DENGUE AND WEST NILE VIRUSES PROTEINS AND GENES CODING THE FOREGOING, AND THEIR USE IN VACCINAL, THERAPEUTIC AND DIAGNOSTIC APPLICATIONS
有权
登革热和西尼氏病毒蛋白质和基因编码前体及其在疫苗，治疗和诊断应用中的应用
- 专利标题： DENGUE AND WEST NILE VIRUSES PROTEINS AND GENES CODING THE FOREGOING, AND THEIR USE IN VACCINAL, THERAPEUTIC AND DIAGNOSTIC APPLICATIONS
- 专利标题（中）： 登革热和西尼氏病毒蛋白质和基因编码前体及其在疫苗，治疗和诊断应用中的应用
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申请号： US12476304申请日： 2009-06-02
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公开(公告)号： US20130089558A1公开(公告)日： 2013-04-11
- 发明人: Frédéric Tangy , PHILIPPE DESPRES , CHANTAL COMBREDET , MARIE PASCALE FRENKIEL
- 申请人： Frédéric Tangy , PHILIPPE DESPRES , CHANTAL COMBREDET , MARIE PASCALE FRENKIEL
- 专利权人： CENTRE NATIONALE DE LA RECHERCHE SCIENTIFIQUE,INSTITUT PASTEUR
- 当前专利权人： CENTRE NATIONALE DE LA RECHERCHE SCIENTIFIQUE,INSTITUT PASTEUR
- 优先权： CA2,420,092 20030226; CA2,432,738 20030620
- 主分类号： A61K39/12
- IPC分类号： A61K39/12 ; C07K14/18
摘要：
The present invention relates to the development of viral vectors expressing different immunogens from the West Nile Encephalitis Virus (WNV) or the Dengue virus which are able to induce protective humoral and cellular immune responses against WNV or Dengue virus infections. More specifically, the present invention relates to three (3) antigens from WNV (the secreted envelope glycoprotein (E), the heterodimer glycoproteins (pre-M-E) and the NSI protein) and from Dengue virus (the secreted envelope glycoprotein (e), the heterodimer glycoproteins (pre-m-e) and the nsl protein) and their use in vaccinal, therapeutic and diagnostic applications.
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