发明申请
US20130090309A1 AMINO-PYRIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS
有权
含氨基吡啶类的吡咯啉类激酶(SYK)抑制剂
- 专利标题: AMINO-PYRIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS
- 专利标题(中): 含氨基吡啶类的吡咯啉类激酶(SYK)抑制剂
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申请号: US13704484申请日: 2012-04-30
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公开(公告)号: US20130090309A1公开(公告)日: 2013-04-11
- 发明人: Eric Thomas Romeo , Michelle R. Machacek , Benjamin Wesley Trotter , Thomas Allen Miller , Brian Michael Andresen , Neville John Anthony , Brandon M. Taoka , Yuan Liu
- 申请人: Eric Thomas Romeo , Michelle R. Machacek , Benjamin Wesley Trotter , Thomas Allen Miller , Brian Michael Andresen , Neville John Anthony , Brandon M. Taoka , Yuan Liu
- 国际申请: PCT/US12/35725 WO 20120430
- 主分类号: A61K31/444
- IPC分类号: A61K31/444 ; A61K31/496 ; A61K45/06 ; A61K31/675 ; C07F5/02 ; A61K31/69 ; C07D417/14 ; C07F9/6558
摘要:
The invention provides certain amino-pyridine-containing compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and n are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase.
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