摘要:
The invention provides certain amino-pyridine-containing compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and n are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase.
摘要:
The invention provides certain amino-pyridine-containing compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and n are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase.
摘要:
The invention provides certain thiazole-substituted aminoheteroaryl compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein X1, X2, X3, X4, Y1, Y2, Y3, Y4, and R4 are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).
摘要:
The present invention provides compounds, compositions and methods for the treatment of prostate cancers, preferably, advanced prostate cancers. The subject invention also provides compounds, compositions and methods for preventing/slowing down/reducing the progress and proliferation of prostate cancer cells. The subject invention further provides compounds, compositions and methods for inhibiting DNA repair within cancer cells to slow tumor growth, preferably, by inhibiting BER capacity, including pol β and LIG I.
摘要:
Embodiment of present invention provide an optical interconnect apparatus. The apparatus includes an optical signal path; a first set of pigtail fibers attached to a first end of the optical signal path via a first wavelength-division-multiplexing (WDM) filter; and a second set of pigtail fibers attached to a second end of the optical signal path via a second WDM filter. Embodiment of present invention further provide an interconnected optical system that includes a first optical transport terminal having a first set of optical signal ports and a second optical transport terminal having a second set of optical signal ports, with the two sets of optical signal ports being interconnected by the optical interconnect apparatus.
摘要:
A communication device comprises a single radio resource unit that is shared by a plurality of virtual modems (VMs), each uniquely associated with a single one of a plurality of SIM cards. Traffic related to the SIM cards are concurrently handled utilizing corresponding VMs. Available radio resource in the single radio resource unit are shared by the VMs based on corresponding VM states, namely, an active state, an idle state and a suspended state. VMs in an idle state concurrently monitor paging events and concurrently perform idle mode procedures such as location updating. VMs not related to an intended traffic are suspended. A VM related to the intended traffic is transitioned from an idle state to an active state to enable the communication for the intended traffic. Once the communication is complete, the suspended VMs are resumed to continue idle mode activities.
摘要:
The present invention provides a compound of Formula 1 as described herein or a pharmaceutically acceptable salt, solvate or ester thereof. The compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same.
摘要:
A telepresence system, a telepresence method, and a video collection device are disclosed. The telepresence system includes a video collection device, a video display device, an audio collection device, an audio player, and an audio and video communication device. The audio and video communication device transmits videos collected by the video collection device on a local end and audios collected by the audio collection device on the local end to a remote end through a network; the video display device and the audio player on the remote end play the images and audios respectively; and the video collection device is a panoramic camera. The technical solution under the present invention overcomes the poor effect of panoramic presence in the existing telepresence system, and improves the telepresence system in terms of depth presence, seamless display and eye contact.
摘要:
Systems and methods are presented to support operation of a multiple subscriber identity module (SIM) device. A first SIM may perform a data transfer or voice call. During the first SIM's data transfer or voice call, transition times are identified to transition communication resources to a second SIM for use in performing a registration update communication with a network controller that supports the second SIM. The registration update communication may include a periodic location update, a periodic routing update, or a periodic tracking update. The multiple SIM device may identify the transition time by obtaining periodic registration timing information from the network controller, configuring a periodic registration timer based on the periodic registration timing information, and setting the transition time as an expiration time of the periodic registration timer.
摘要:
A video communication method, device, and system are provided, which relate to the filed of video communications, so as to solve problems that currently scenes of two parties of communication need special arrangement to improve sense of reality and scene contents cannot be displayed in a 3D video mode. Therefore, scenes of two parties of communication do not need special arrangement to improve the sense of reality of users, and the scene contents can be displayed in a 3D video mode. The video communication method, device, and system are applicable to video communication such as common video chat, video telephony, and video conference.