发明申请
- 专利标题: PAN-LYSSAVIRUS VACCINES AGAINST RABIES
- 专利标题(中): PAN-LYSSAVIRUS疫苗对兔子
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申请号: US13806622申请日: 2011-06-23
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公开(公告)号: US20130095137A1公开(公告)日: 2013-04-18
- 发明人: Xianfu Wu , Charles E. Rupprecht , Ivan V. Kuzmin
- 申请人: Xianfu Wu , Charles E. Rupprecht , Ivan V. Kuzmin
- 申请人地址: US GA Atlanta
- 专利权人: The Government of the United States of America as Represented by the Secretary of the Department of
- 当前专利权人: The Government of the United States of America as Represented by the Secretary of the Department of
- 当前专利权人地址: US GA Atlanta
- 国际申请: PCT/US11/41579 WO 20110623
- 主分类号: A61K39/205
- IPC分类号: A61K39/205
摘要:
Described herein are recombinant rabies viruses encoding rabies virus glycoprotein and at least one heterologous glycoprotein from another lyssavirus, such as Mokola virus, Lagos bat virus and/or West Caucasian bat virus. In particular embodiments, the recombinant rabies virus includes two or three heterologous lyssavirus glycoproteins. The disclosed recombinant rabies viruses can be used as pan-lyssavirus vaccines to provide protection against lyssaviruses that cause rabies.
公开/授权文献
- US09248179B2 Pan-lyssavirus vaccines against rabies 公开/授权日:2016-02-02
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