发明申请
US20130096183A1 TREATMENT OF SODIUM CHANNEL, VOLTAGE-GATED, ALPHA SUBUNIT (SCNA) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO SCNA
有权
通过抑制自然抗原转录物到SCNA，治疗钠通道，电压门控，ALPHA亚型（SCNA）相关疾病
- 专利标题： TREATMENT OF SODIUM CHANNEL, VOLTAGE-GATED, ALPHA SUBUNIT (SCNA) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO SCNA
- 专利标题（中）： 通过抑制自然抗原转录物到SCNA，治疗钠通道，电压门控，ALPHA亚型（SCNA）相关疾病
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申请号： US13805745申请日： 2011-06-23
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公开(公告)号： US20130096183A1公开(公告)日： 2013-04-18
- 发明人: Joseph Collard , Olga Khorkova Sherman , Belinda De Leon , Carlos Coito , Jane H. Hsiao
- 申请人： Joseph Collard , Olga Khorkova Sherman , Belinda De Leon , Carlos Coito , Jane H. Hsiao
- 申请人地址： US FL Miami
- 专利权人： CuRNA, Inc.
- 当前专利权人： CuRNA, Inc.
- 当前专利权人地址： US FL Miami
- 国际申请： PCT/US2011/041664 WO 20110623
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; C12Q1/68
摘要：
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Sodium channel, voltage-gated, alpha subunit (SCNA), in particular, by targeting natural antisense polynucleotides of Sodium channel, voltage-gated, alpha subunit (SCNA). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of SCNA.
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