发明申请
- 专利标题: BIPYRIDYL DERIVATIVES
- 专利标题(中): BIPYRIDYL衍生物
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申请号: US13808369申请日: 2011-06-07
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公开(公告)号: US20130102608A1公开(公告)日: 2013-04-25
- 发明人: Guenter Hoelzemann , Dieter Dorsch , Alfred Jonczyk , Christiane Amendt , Frank Zenke
- 申请人: Guenter Hoelzemann , Dieter Dorsch , Alfred Jonczyk , Christiane Amendt , Frank Zenke
- 申请人地址: DE DARMSTADT
- 专利权人: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
- 当前专利权人: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
- 当前专利权人地址: DE DARMSTADT
- 优先权: EP10006927.7 20100705
- 国际申请: PCT/EP2011/002788 WO 20110607
- 主分类号: C07D401/14
- IPC分类号: C07D401/14 ; A61K45/06 ; A61K31/496 ; A61K31/4545 ; A61K31/5377 ; A61K31/444
摘要:
The present invention relates to novel bipyridyl derivatives of formula (I) and to the use of such compounds in which the inhibition, regulation and/or modulation of signal transduction by ATP consuming proteins like kinases plays a role, particularly to inhibitors of TGF-beta receptor kinases, and to the use of such compounds for the treatment of kinase-induced diseases, in particular for the treatment of tumors.
公开/授权文献
- US08846931B2 Bipyridyl derivatives 公开/授权日:2014-09-30
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