In a method for processing location holes of a motherboard, a motherboard image of the motherboard is converted into a grayscale image. The grayscale image is normalized and converted into a binary image. Closed contours in the binary image and a minimum circumscribed circle of each of the closed contours are acquired from the binary image. A radius, a circumcenter coordinate and an average pixel value of each minimum circumscribed circle, and an average pixel value of the binary image are calculated. One or more minimum circumscribed circles are selected if each of the selected minimum circumscribed circles has a radius in a predetermined radius range and an average pixel value that is greater than the average pixel value of the binary image.