发明申请
- 专利标题： SUBSTITUTED IMIDAZOQUINOLINE DERIVATIVES AS KINASE INHIBITORS
- 专利标题（中）： 取代的咪唑啉醇衍生物作为激酶抑制剂
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申请号： US13810431申请日： 2011-07-15
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公开(公告)号： US20130116248A1公开(公告)日： 2013-05-09
- 发明人: Sanjay Kumar , Rajiv Sharma , Robert Zahler , Bichismita Sahu , Veena R. Agarwal , Nishigandha Naik
- 申请人： Sanjay Kumar , Rajiv Sharma , Robert Zahler , Bichismita Sahu , Veena R. Agarwal , Nishigandha Naik
- 申请人地址： IN Mumbai
- 专利权人： PIRAMAL ENTERPRISES LIMITED
- 当前专利权人： PIRAMAL ENTERPRISES LIMITED
- 当前专利权人地址： IN Mumbai
- 国际申请： PCT/IB11/53161 WO 20110715
- 主分类号： C07D471/04
- IPC分类号： C07D471/04
摘要：
The present invention relates to substituted imidazo[4,5-c]quinoline derivatives, the compounds of formula (I), wherein R1, R2, R3, R4, R5, R6 and R7 are as defined in the specification, processes for their preparation, pharmaceutical compositions comprising compounds of formula (I), and their use in the treatment of diseases or disorders mediated by one or more kinases, particularly proliferative diseases or disorders such as cancer. These compounds can also be used in the treatment of inflammatory diseases and angiogenesis related disorders.
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