发明申请
- 专利标题: CANCER TREATMENT WITH RECOMBINANT VECTOR
- 专利标题(中): 癌症治疗与重组载体
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申请号: US13638490申请日: 2011-03-29
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公开(公告)号: US20130130986A1公开(公告)日: 2013-05-23
- 发明人: Harry E. Gruber , Douglas J. Jolly , Omar Perez , Derek G. Ostertag , Joan M. Robbins
- 申请人: Harry E. Gruber , Douglas J. Jolly , Omar Perez , Derek G. Ostertag , Joan M. Robbins
- 申请人地址: US CA San Diego
- 专利权人: TOCAGEN INC.
- 当前专利权人: TOCAGEN INC.
- 当前专利权人地址: US CA San Diego
- 国际申请: PCT/US11/30402 WO 20110329
- 主分类号: A61K48/00
- IPC分类号: A61K48/00 ; A61K38/22
摘要:
This disclosure provides modified cytosine deaminases(CDs). The disclosure further relates to cells and vector expressing or comprising such modified CDs and methods of using such modified CDs in the treatment of disease and disorders. It further provides use of such modified CDs with a thymosin-alpha-1 polypeptide in the treatment of disease and disorders.
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