发明申请
- 专利标题： CARBOXAMIDES AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS
- 专利标题（中）： 碳酰胺作为电压门控通道的抑制剂
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申请号： US13575912申请日： 2011-02-16
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公开(公告)号： US20130131035A1公开(公告)日： 2013-05-23
- 发明人: Howard Bregman , John L. Buchanan , Nagasree Chakka , Erin F. Dimauro , Bingfan Du , Hanh Nho Nguyen , Xiao Mei Zheng
- 申请人： Howard Bregman , John L. Buchanan , Nagasree Chakka , Erin F. Dimauro , Bingfan Du , Hanh Nho Nguyen , Xiao Mei Zheng
- 申请人地址： US CA Thousand Oaks
- 专利权人： AMGEN INC.
- 当前专利权人： AMGEN INC.
- 当前专利权人地址： US CA Thousand Oaks
- 国际申请： PCT/US11/25092 WO 20110216
- 主分类号： C07D471/10
- IPC分类号： C07D471/10 ; C07D401/04 ; C07D403/04 ; C07D251/48
摘要：
The present invention provides compounds that are inhibitors of voltage-gated sodium channels (Nav), in particular Nav 1.7, and are therefore useful for the treatment of diseases treatable by inhibition of these channels, in particular, chronic pain disorders. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.
公开/授权文献
- US09334269B2 Carboxamides as inhibitors of voltage-gated sodium channels 公开/授权日：2016-05-10
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