发明申请
- 专利标题: PHARMACEUTICAL FORMULATION OF APOMORPHINE FOR BUCCAL ADMINISTRATION
- 专利标题(中): 药物制剂用于药物治疗
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申请号: US13669148申请日: 2012-11-05
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公开(公告)号: US20130131098A1公开(公告)日: 2013-05-23
- 发明人: Anthony Clarke
- 申请人: Anthony Clarke
- 申请人地址: IE Ballsbridge
- 专利权人: Amarin Pharmaceuticals Ireland Limited
- 当前专利权人: Amarin Pharmaceuticals Ireland Limited
- 当前专利权人地址: IE Ballsbridge
- 优先权: GB0509317.4 20050506; GBPCT/GB2006/001665 20060508
- 主分类号: A61K31/435
- IPC分类号: A61K31/435 ; A61K9/00
摘要:
The present invention provides a kit comprising, in separate compartments of a container, the following components (a) and (b): (a) a combination of apomorphine or a pharmaceutically acceptable acid addition salt thereof and a pharmaceutically acceptable excipient or carrier; and (b) a solution which comprises a diluent and a pH modifying agent; the components being presented such that they can be combined at the point of use into a formulation which is adjusted to a pH ranging from mildly acidic to alkaline and which is suitable for buccal administration. The formulation is useful in treating Parkinson's disease and in promoting sexual function.
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