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公开(公告)号：US20240216322A1
公开(公告)日：2024-07-04
申请号：US18603789
申请日：2024-03-13
发明人： Jonathan Rowe
IPC分类号： A61K31/232 , A61K9/00 , A61K9/48 , A61K31/20 , A61K31/202 , A61K31/355 , A61K45/06 , A61K47/22 , A61P3/06
CPC分类号： A61K31/232 , A61K9/0053 , A61K9/48 , A61K9/4808 , A61K9/4816 , A61K9/4825 , A61K31/20 , A61K31/202 , A61K31/355 , A61K45/06 , A61K47/22 , A61P3/06
摘要： In various embodiments, the present invention provides pharmaceutical compositions comprising fatty acids and methods for treating subjects using same.
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公开(公告)号：US11986452B2
公开(公告)日：2024-05-21
申请号：US17723598
申请日：2022-04-19
发明人： Paresh Soni
IPC分类号： A61K31/232 , A61P9/10
CPC分类号： A61K31/232 , A61P9/10
摘要： In various embodiments, the present disclosure provides methods reducing the risk of heart failure in a subject on statin therapy by administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
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公开(公告)号：US11712428B2
公开(公告)日：2023-08-01
申请号：US17087759
申请日：2020-11-03
发明人： Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni , Jonathan Rowe
IPC分类号： A61K31/232 , A61K31/202 , A61K31/355 , A61K45/06 , A61P3/06 , A61P9/12 , A61P9/14 , A61K9/48
CPC分类号： A61K31/232 , A61K31/202 , A61K31/355 , A61K45/06 , A61P3/06 , A61P9/12 , A61P9/14 , A61K9/4875 , A61K31/355 , A61K2300/00 , A61K31/202 , A61K2300/00 , A61K31/232 , A61K2300/00
摘要： In various embodiments, the present invention provides pharmaceutical compositions and methods for treating cardiovascular-related disease.
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公开(公告)号：US20230210806A1
公开(公告)日：2023-07-06
申请号：US17884680
申请日：2022-08-10
发明人： Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni , Mehar Manku
IPC分类号： A61K31/232 , A61P9/10 , C07C57/03 , A61P3/06 , A61K31/202 , A61K31/366 , A61K31/40 , A61K31/505 , A61K9/48
CPC分类号： A61K31/232 , A61P9/10 , C07C57/03 , A61P3/06 , A61K31/202 , A61K31/366 , A61K31/40 , A61K31/505 , A61K9/48
摘要： In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
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公开(公告)号：US11446269B2
公开(公告)日：2022-09-20
申请号：US16188905
申请日：2018-11-13
IPC分类号： A61K31/202 , A61K31/40 , A61P9/10 , A61P9/02
摘要： In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of reducing or preventing small dense LDL (“sdLDL”) oxidation in a subject, the method comprising administering to the subject a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
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公开(公告)号：US11285127B2
公开(公告)日：2022-03-29
申请号：US16897663
申请日：2020-06-10
发明人： Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni , Mehar Manku
IPC分类号： A61K31/232 , G01N33/92 , G01N33/96
摘要： In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
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公开(公告)号：US20220079906A1
公开(公告)日：2022-03-17
申请号：US17457126
申请日：2021-12-01
发明人： Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni , Mehar Manku
IPC分类号： A61K31/202 , A61K45/06 , A61K31/222 , A61K31/232 , A61K31/40 , A61K31/505 , A61K9/48 , A61K47/22 , A61K47/26 , A61K47/34
摘要： The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
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公开(公告)号：US11229618B2
公开(公告)日：2022-01-25
申请号：US16197924
申请日：2018-11-21
发明人： Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni , Mehar Manku
IPC分类号： A61K31/202
摘要： In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
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公开(公告)号：US20220000829A1
公开(公告)日：2022-01-06
申请号：US17469051
申请日：2021-09-08
发明人： Paresh Soni
IPC分类号： A61K31/232 , A61P9/10 , A61K9/00
摘要： In various embodiments, the present disclosure provides methods reducing the risk of cardiovascular events in a subject on statin therapy by administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
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公开(公告)号：US20210379002A1
公开(公告)日：2021-12-09
申请号：US17393213
申请日：2021-08-03
发明人： Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni , Mehar Manku
IPC分类号： A61K31/202 , A61K45/06 , A61K31/222 , A61K31/232 , A61K31/40 , A61K31/505 , A61K9/48 , A61K47/22 , A61K47/26 , A61K47/34
摘要： The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
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