发明申请
- 专利标题： HISTONE DEMETHYLASE INHIBITORS AND METHODS FOR USING THE SAME
- 专利标题（中）： 组氨酸脱乙酰酶抑制剂及其使用方法
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申请号： US13691507申请日： 2012-11-30
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公开(公告)号： US20130137720A1公开(公告)日： 2013-05-30
- 发明人: Xiang Wang , Wenqing Xu
- 申请人： Xiang Wang , Wenqing Xu
- 申请人地址： US CO Denver
- 专利权人： The Regents of the University of Colorado, a body corporated
- 当前专利权人： The Regents of the University of Colorado, a body corporated
- 当前专利权人地址： US CO Denver
- 主分类号： C07C271/30
- IPC分类号： C07C271/30 ; C07D211/28 ; C07D215/38 ; C07C271/12 ; C07C271/28
摘要：
The present invention provides compounds, or derivatives or prodrugs thereof, that comprise a methyllysine mimic, and an α-ketoglutarate mimic that are attached through a linker and methods for using and producing the same. In some embodiments, compounds of the invention are of the formula: M-L-K, or a derivative or a prodrug thereof, wherein M is a methyllysine mimic, L is a linker, and K is an α-ketoglutarate mimic.