发明申请
US20130150555A1 COMPOSITION CONTAINING INDUCER OF SIRT1 EXPRESSION FOR PREVENTING OR TREATING SEPSIS OR SEPTIC SHOCK
有权
包含SIRT1表达诱发剂的组合物，用于预防或治疗食欲或分解性震动
- 专利标题： COMPOSITION CONTAINING INDUCER OF SIRT1 EXPRESSION FOR PREVENTING OR TREATING SEPSIS OR SEPTIC SHOCK
- 专利标题（中）： 包含SIRT1表达诱发剂的组合物，用于预防或治疗食欲或分解性震动
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申请号： US13818847申请日： 2012-02-17
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公开(公告)号： US20130150555A1公开(公告)日： 2013-06-13
- 发明人: Myung Kwan Han , Chae Hwa Yoo , Eun Kyung Song , Seung Ok Lee
- 申请人： Myung Kwan Han , Chae Hwa Yoo , Eun Kyung Song , Seung Ok Lee
- 申请人地址： KR Jeonju-si, Jeonbuk
- 专利权人： STEMDER INC.
- 当前专利权人： STEMDER INC.
- 当前专利权人地址： KR Jeonju-si, Jeonbuk
- 优先权： KR10-2011-0014474 20110218; KR10-2012-0016524 20120217
- 国际申请： PCT/KR12/01225 WO 20120217
- 主分类号： A61K38/21
- IPC分类号： A61K38/21
摘要：
The present invention relates to a composition containing an inducer of SIRT1 (silent mating type information regulation 2 homolog) expression for preventing or treating sepsis or septic shock. The inducer of SIRT1 expression can remarkably reduce the mortality caused by sepsis or septic shock by reducing pro-inflammatory cytokines and increasing anti-inflammatory cytokines. Therefore, the inducer of SIRT1 expression is useful for preventing or treating sepsis or septic shock.
公开/授权文献
- US09913880B2 Method of treating sepsis or septic shock 公开/授权日：2018-03-13